Mutation Mode.png

Mutation Mode is a round-based mode that throws soldiers into quarantined territories in an attempt to survive armies of playable mutants characters. The mode is available in every version of the game under the following alias:

  • Mutation Mode (Most Versions).
  • Zombie Mode (Philippines, Vietnam, Indonesia).
  • Nano Mode (South Korea).
  • Biochemical Mode (China).
  • Pandemic Mode (Japan).


Both factions, now teaming up, must prepare for the incoming infection as they have only twenty seconds to find a decent spot to defend in their current quarantined zone. Once the countdown is done, two soldiers will turn into mutants and attempt to spread the infection onto every soldier. It is possible to completely eradicate every mutant as they do not respawn once killed.

Main article: Mutants
Mutants have a lot of health points (starting at 2000), but they can only use melee range attacks (their own claws or the Mutation Spike). The two "host" mutants automatically start at berserk level, all other infected mutants will start at a normal level and have to work their way up to use their special skills.  Mutants can also evolve, absorb or recover health if they want to survive as much as they can. When mutants are evolving, they gain a few more health points and will eventually be able to use special skills depending on their current mutant.
  • Evolution: As mutants infect others they will evolve into other forms with more health.
  • Absorption: mutants can absorb other mutant dead bodies to evolve.
  • Recovery: When standing still for several seconds, the mutant will then regenerate health.

Mutants Names / Skills Information
Icon Dread.png Dreads Dreads have limited attack range, even though they have claws. But, their attack speed is quite fast.
Speed Boost
Icon Mutants.png Mutants While their attacks speed are slower, they have longer reach than the Dreads.
Speed Boost
Icon Maiden.png Maiden Mutated woman nurse with partial invisibility abilities as well as being able to jump higher than others.
High Jump / Invisibility

Mutants Names / Skills Information
Icon Smoke.png Smoke Mutated general officer with a weird backpack that spews out smoke screens to blind soldiers.
Smoke Screen
Icon Assassins.png Assassins Cunning mutant who managed to acquire repulse grenades that disrupts soldiers positions.
Repulse Grenades
Nano Corpse.png Enchantress Reanimated corpse seeking for life essences. She acts like Maidens, but can jumps way higher.
High Jump / Higher Jump.

Icons Items Information
ItemIcon 333.png Mutation Spike This melee weapons has faster attack speed and longer reach; also gives double evolution points.
ItemIcon 399.png Mutation Grenade A biochemical grenade that only affects mutants, which deals with massive damages.
ItemIcon 334.png Mutation Mags It gives half of the ammo back on top of the initial ammunition reserve (it stacks with other mags).
ItemIcon 335.png Mutation Jacket Jacket that gives an additional shot before getting infected / Armor points for mutants.
ItemIcon 425.png Knock Back Reduce An item that reduces the stun and knockback effects on mutants.

If soldiers ever need additional ammunition or weapons, they will be able to collect supply crates that drop every 50 seconds (2:10, 1:20 and 0:30). Additionally, there's a Christmas version of the supply crates, however, it hasn't been brought back for a while. Whatever these boxes contain vary in every version; these are the common items:

  • Ammo Refills: Refills whatever primary weapons the soldiers are currently using.
  • M60-Adv: Variant of the M60 machine gun with a lot more ammunition to defend.
  • RPK: Machine gun with strong firepower, but lacks in the ammunition department.
  • Gatling Gun: An extremely heavy gun but quite deadly and effective in combat.
  • Mutation Grenade: Special grenade that deals tons of damages to the mutants.
  • Mutation Jacket: Help you survive longer.
  • Others: Versions vary with different Rifles, SMGs, secondaries and grenades.

The mode offers a great variety of quarantined type maps with various spots available to hold off the forthcoming horde of mutants. These maps are all also available in both Hero Mode and Hero Mode X variants:

Maps Description Maps Description
Rock Hewn Ruin.png Large ruin site located deep into the jungle. LobbyMap53.png The ruins of a Lost City recently discovered.
LobbyMap76.png A large abandoned and empty military R&D base. LobbyMap57.png Large Colosseum located in Merida.
LobbyMap38.png Desert area with the familiar territory (China only). LobbyMap72.png Large abandoned mall with accessible shops.

The mode offers a great variety of quarantined type maps with various spots available to hold off the forthcoming horde of mutants. These maps are all also available in both Hero Mode and Hero Mode X variants:

Maps Description Maps Description
LobbyMap52.png Classic S&D map turned into a quarantined zone. LobbyMap54.png Secret underground lab located in Northern Africa.
Vault.png Small observatory with low-gravity in the center. Tranquility .png Small Asian village with various palaces.
LobbyMap41.png A vast suburb surrounded by various buildings. - -



Main Article: Counter-Strike Online

This mode is based on Counter-Strike Online's Zombie: The Original (formerly known as Zombie Mod 1 in the past). However, CSO introduced new features in a new mode named Zombie: The Mutation (Zombie Mod 2), which included: Evolution, Absorbing, Supply Crates, Health Recovery and new type of playable Zombies characters.

Crossfire China, Vietnam & Japan were added the same Zombie: The Original mode for their version, featured a slightly different Dread model and no Supply Box, Evolution, Absorption, Health Recovery, and Mutants' skills, but it was replaced by recently Mutation Mode.

CrossFire added the same, by adding a new Mutant (and more later on) and the aforementioned features, but decided to add it to the original mode instead of making a totally new one as CSO did. Surprisingly, they even used most of their Zombies ideas for the different Mutants available in Mutation Modes here.

Their next installment for this mode also made its way onto CrossFire; CSO's Zombie: The Hero (Zombie Mod 3) brought Hero Mode to CrossFire. Although they did more variants, CrossFire started to make their own, starting with a mode based on previous ones but with a new set of rules and characters, thus, Hero Mode X was born.

VTC (publishers of the Vietnamese version) decided to use CSO's original mode names for every variation in their version, starting with Zombie Mod 2. However, it obviously left a gap at the beginning, as CrossFire did not make a separate variation only for the sole purpose of adding new features as they simply ported it to Mutation Mode.

Almost all players often camp in this mode. The others run away around the map with moving skills so that the mutants can't get them. We call it parkour.

After Mutation Knight Mode, the next variant of Mutation Mode is Mutant Escape Mode. It is obviously inspired by CSO's Zombie Escape. Its playing style is similar to CSO's, but with increased damage for soldiers' weapons (which can reach up to 800%); furthermore, there are many warp portal that soldiers must open to continue the run.


  • Originally when a soldier becomes the Last Man Standing, he will emit a blue aurora and his HPs increase to 1000. This allows him to parkour freely without worrying about fall damage, but at the same time attract mutants' attention much more easily.
  • In CF Vietnam, there are lacks of Maiden, Smoke, Assassin, and Enchantress's appearance sounds. The publisher doesn't notice this, even though this mode has been played every day; however, this can be fixed by using the sound files from other CF versions to add/overwrite CF Vietnam's.
    • After the Nano Kitchen map updated, the Maiden and Enchantress's appearance sounds have been added into the game, however, the Smoke and Assassin's one is still missing.
  • During the gameplay, a newly infected mutant will hear the breath sound only on the player. But in expanded mutation mode variants like Hero Mode X, Mutation Knight Mode, Mutant Escape Mode, etc. it won't be heard anymore, this might been forgotten to add it.
  • When this mode was released in CF Vietnam, there was a bug in which soldiers throw a grenade to other soldiers before transforming to mutant; and if that soldiers are infected or transform the first mutant; he/she will kill soldiers by a grenade. This bug has been fixed in later patches.


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